{"id":5353,"date":"2022-09-07T19:54:37","date_gmt":"2022-09-07T19:54:37","guid":{"rendered":"https:\/\/njcts.org\/tsparents\/?p=5353"},"modified":"2024-04-08T19:27:25","modified_gmt":"2024-04-08T19:27:25","slug":"unraveling-pans-panda-ocd-and-ts","status":"publish","type":"post","link":"https:\/\/njcts.org\/tsparents\/unraveling-pans-panda-ocd-and-ts\/","title":{"rendered":"Unraveling PANS\/PANDA, OCD and TS"},"content":{"rendered":"\n<p>People who have tics or Tourette Syndrome often also have OCD-like behaviors. Those affected with <a href=\"https:\/\/www.nature.com\/articles\/s41398-021-01700-4\" target=\"_blank\" rel=\"noreferrer noopener\">Obsessive-compulsive disorder (OCD)<\/a> have agonizing irrational thoughts (obsessions) that lead to a strong emotional reaction, such as anxiety or disgust, and they often use repeated excessive behaviors (compulsions) to reduce this anxiety.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-wp-embed is-provider-ts-parents-online wp-block-embed-ts-parents-online\"><div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"wp-embedded-content\" data-secret=\"VcCd3pjU5X\"><a href=\"https:\/\/njcts.org\/tsparents\/20-facts-about-tourette-syndrome-you-may-or-may-not-know\/\">20 facts about Tourette Syndrome you may or may not know<\/a><\/blockquote><iframe class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" title=\"&#8220;20 facts about Tourette Syndrome you may or may not know&#8221; &#8212; TS Parents Online\" src=\"https:\/\/njcts.org\/tsparents\/20-facts-about-tourette-syndrome-you-may-or-may-not-know\/embed\/#?secret=WBMhHpXHJe#?secret=VcCd3pjU5X\" data-secret=\"VcCd3pjU5X\" width=\"600\" height=\"338\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe>\n<\/div><\/figure>\n\n\n\n<p>In 2015, NJCTS published these general statistics on comorbidities in TS:<\/p>\n\n\n\n<ul>\n<li>25%-50% of people with Tourette or Chronic Tic Disorder meet the criteria for a formal diagnosis of OCD<\/li>\n\n\n\n<li>80% of people with Tourette or Chronic tic disorder may have obsessive compulsive behaviors<\/li>\n\n\n\n<li>30% of people with OCD have a family history of co-occurring Tourette or Chronic Tic Disorder<\/li>\n<\/ul>\n\n\n\n<p>A lot of recent research including twin studies, neuroimaging studies, and a genome-wide complex trait analysis, suggest that there is a significant genetic association between TS and OCD.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-wp-embed is-provider-ts-parents-online wp-block-embed-ts-parents-online\"><div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"wp-embedded-content\" data-secret=\"vYkyv9ggCw\"><a href=\"https:\/\/njcts.org\/tsparents\/what-are-the-chances-that-my-son-or-daughter-will-have-ts-and-ocd\/\">What are the chances that my son or daughter will have TS and OCD?<\/a><\/blockquote><iframe class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" title=\"&#8220;What are the chances that my son or daughter will have TS and OCD?&#8221; &#8212; TS Parents Online\" src=\"https:\/\/njcts.org\/tsparents\/what-are-the-chances-that-my-son-or-daughter-will-have-ts-and-ocd\/embed\/#?secret=3Fz5giYocZ#?secret=vYkyv9ggCw\" data-secret=\"vYkyv9ggCw\" width=\"600\" height=\"338\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe>\n<\/div><\/figure>\n\n\n\n<p>However, recently it was reported that Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal infection (PANDAS) and Pediatric Acute onset Neuropsychiatric Syndrome (PANS) can lead to an onset of OCD and tics. <a href=\"https:\/\/www.webmd.com\/children\/what-is-pandas-syndrome\" target=\"_blank\" rel=\"noreferrer noopener\">PANDAS<\/a> can occur when an infection, such as strep, causes the immune system to attack the body\u2019s healthy cells, often, cells in the brain. The strep bacteria disguise themselves to look like normal cells. When the immune system eventually finds and fights them, it sometimes also fights the cells that the strep is imitating. Unlike PANDAS, which only comes from strep, PANS has multiple etiologies and disease mechanisms.<\/p>\n\n\n\n<p><strong>It is frequently asked if Tourette Syndrome is related to PANDAS or PANS<\/strong>. The symptoms may seem similar and a lack of understanding about these complex disorders can result in misdiagnosis. Tourette Syndrome is a neurological disorder. Although the cause is clearly known, genetic studies indicate that TS is inherited as a dominant gene. A person with TS has about a 50 percent chance of passing the gene to one or more of his\/her children. This genetic predisposition may express itself as TS, a milder tic disorder or obsessive compulsive symptoms with no tics at all. <a href=\"https:\/\/njcts.org\/what-is-tourette-syndrome\/#FAQ\" target=\"_blank\" rel=\"noreferrer noopener\">TS is a diagnosis that doctors make after verifying that the patient has had both motor and vocal tics for at least 1 year<\/a>.<\/p>\n\n\n\n<p>With <a href=\"https:\/\/www.webmd.com\/children\/what-is-pandas-syndrome\">PAN or PANDAS,<\/a> your child may seem to turn into a different person overnight, becoming moody, anxious, aggressive, displaying obsessive compulsive behaviors, and dealing with body movements they can\u2019t control.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.webmd.com\/children\/what-is-pandas-syndrome\">Stanford Medicine defines the syndromes this way<\/a>:<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>\u201cPediatric Acute-onset Neuropsychiatric Syndrome (PANS) is a clinical diagnosis given to children who have a dramatic \u2013 sometimes overnight \u2013 onset of neuropsychiatric symptoms including obsessions\/compulsions or food restriction. They are often diagnosed with obsessive-compulsive disorder (OCD) or an eating disorder, but the sudden onset of symptoms separates PANS from these other disorders. In addition, they may have symptoms of depression, irritability, anxiety, and have difficulty with schoolwork. The cause of PANS is unknown in most cases but is thought to be triggered by infections, metabolic disturbances, and other inflammatory reactions.<\/p>\n\n\n\n<p>Like <a href=\"https:\/\/med.stanford.edu\/pans.html\" target=\"_blank\" rel=\"noreferrer noopener\">PANS<\/a>, children with Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infections (PANDAS) have an acute onset \u2013 within 2 to 3 days \u2013 of neuropsychiatric symptoms, specifically OCD or tics (involuntary, purposeless movements). However, PANDAS patients test positive for a recent streptococcal infection, such as strep throat, peri-anal strep or scarlet fever. Like PANS patients, they also may suffer from uncontrollable emotions, irritability, anxiety and loss of academic ability and handwriting skills. Although PANDAS was identified as a medical syndrome more than a decade before PANS, it has been classified as a subset of PANS. To date, PANDAS is the only known subset of PANS, but we may discover more causes in the future.\u201d<\/p>\n<cite><a href=\"https:\/\/med.stanford.edu\/\" target=\"_blank\" rel=\"noreferrer noopener\">Stanford Medical<\/a><\/cite><\/blockquote>\n\n\n\n<p>A test for the strep bacteria or a history of the bacteria is necessary to confirm your child has PANDAS, which can mimic other disorders. If your child doesn\u2019t or didn&#8217;t have strep, they don\u2019t have PANDAS, but he or she could be having the symptoms because of PANS. The symptoms are similar, but they may be triggered by something other than strep. Similarly, if the child\u2019s symptoms came on suddenly and reached peak severity within 24-48 hours, the diagnoses of PANS and PANDAS should be considered.<\/p>\n\n\n\n<p>People with PANS\/PANDAS can experience symptoms that do not typically occur in people with Tourette Syndrome. Children with PANS\/PANDAS sometimes experience a personality change not usually seen in people with TS. Physical symptoms such as increased urinary frequency, involuntary urinations, difficulty swallowing, dilated pupils, and other symptoms may also occur.<\/p>\n\n\n\n<p>However, some people PANS\/PANDAS may present predominantly with tics, OCD, and ADHD, so the case may look very similar to TS except for the timing and possibly the existence of strep. Antibiotics often reduced or resolve PANS symptoms, whereas they do not have the same effect on Tourette Syndrome symptoms.<\/p>\n\n\n\n<p>Ultimately, receiving the proper diagnosis will result in the correct care. A thorough understanding of the timing of the onset of symptoms, and any underlying causes such as strep is necessary for reaching the correct conclusion. For an in-depth analysis of PANS\/PANDAS and the overlap with other syndromes, visit<a href=\"https:\/\/aspire.care\/families-parents-caregivers\/pans-pandas-and-tourette-syndrome-the-overlap\/\"> Aspire Care<\/a> and<a href=\"https:\/\/med.stanford.edu\/pans.html\"> Stanford Medicine<\/a><\/p>\n<div class=\"fb-background-color\">\n\t\t\t  <div \n\t\t\t  \tclass = \"fb-comments\" \n\t\t\t  \tdata-href = \"https:\/\/njcts.org\/tsparents\/unraveling-pans-panda-ocd-and-ts\/\"\n\t\t\t  \tdata-numposts = \"10\"\n\t\t\t  \tdata-lazy = \"true\"\n\t\t\t\tdata-colorscheme = \"light\"\n\t\t\t\tdata-order-by = \"social\"\n\t\t\t\tdata-mobile=true>\n\t\t\t  <\/div><\/div>\n\t\t  <style>\n\t\t    .fb-background-color {\n\t\t\t\tbackground:  !important;\n\t\t\t}\n\t\t\t.fb_iframe_widget_fluid_desktop iframe {\n\t\t\t    width: 100% !important;\n\t\t\t}\n\t\t  <\/style>\n\t\t  ","protected":false},"excerpt":{"rendered":"<p>People who have tics or Tourette Syndrome often also have OCD-like behaviors. Those affected with Obsessive-compulsive disorder (OCD) have agonizing irrational thoughts (obsessions) that lead to a strong emotional reaction, such as anxiety or disgust, and they often use repeated&hellip; <a href=\"https:\/\/njcts.org\/tsparents\/unraveling-pans-panda-ocd-and-ts\/\" class=\"more-link\">Continue Reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":524,"featured_media":5226,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[9,10],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.7 (Yoast SEO v22.7) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Unraveling PANS\/PANDA, OCD and TS - TS Parents Online<\/title>\n<meta name=\"description\" content=\"Recently it was reported that PANDAS Associated with Streptococcal infection and PANS can lead to an onset of OCD and tics similar to TS\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/njcts.org\/tsparents\/unraveling-pans-panda-ocd-and-ts\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Unraveling PANS\/PANDA, OCD and TS\" \/>\n<meta property=\"og:description\" content=\"Recently it was reported that PANDAS Associated with Streptococcal infection and PANS can lead to an onset of OCD and tics similar to TS\" \/>\n<meta property=\"og:url\" content=\"https:\/\/njcts.org\/tsparents\/unraveling-pans-panda-ocd-and-ts\/\" \/>\n<meta property=\"og:site_name\" content=\"TS Parents Online\" \/>\n<meta property=\"article:author\" content=\"https:\/\/www.facebook.com\/TouretteSyndrome\/\" \/>\n<meta property=\"article:published_time\" content=\"2022-09-07T19:54:37+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-04-08T19:27:25+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/njcts.org\/tsparents\/wp-content\/uploads\/sites\/7\/2021\/08\/NJCTS_logo.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1080\" \/>\n\t<meta property=\"og:image:height\" content=\"537\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"NJCTS staff\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@https:\/\/twitter.com\/NJCTS\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"NJCTS staff\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/njcts.org\/tsparents\/unraveling-pans-panda-ocd-and-ts\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/njcts.org\/tsparents\/unraveling-pans-panda-ocd-and-ts\/\"},\"author\":{\"name\":\"NJCTS staff\",\"@id\":\"https:\/\/njcts.org\/tsparents\/#\/schema\/person\/c75a13a1c5e3df595f0f64bcfaea0c17\"},\"headline\":\"Unraveling PANS\/PANDA, OCD and TS\",\"datePublished\":\"2022-09-07T19:54:37+00:00\",\"dateModified\":\"2024-04-08T19:27:25+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/njcts.org\/tsparents\/unraveling-pans-panda-ocd-and-ts\/\"},\"wordCount\":856,\"commentCount\":1,\"publisher\":{\"@id\":\"https:\/\/njcts.org\/tsparents\/#organization\"},\"image\":{\"@id\":\"https:\/\/njcts.org\/tsparents\/unraveling-pans-panda-ocd-and-ts\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/njcts.org\/tsparents\/wp-content\/uploads\/sites\/7\/2021\/08\/NJCTS_logo.png\",\"articleSection\":[\"Parents\",\"Professionals\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/njcts.org\/tsparents\/unraveling-pans-panda-ocd-and-ts\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/njcts.org\/tsparents\/unraveling-pans-panda-ocd-and-ts\/\",\"url\":\"https:\/\/njcts.org\/tsparents\/unraveling-pans-panda-ocd-and-ts\/\",\"name\":\"Unraveling PANS\/PANDA, OCD and TS - 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