The literature on Clonidine says that, for some people, it increases the severity of tics. Well, I’ve been taking it for almost two years now and I believe I discovered something about how it interacts with my body.
Ever since I was put on Clonidine, I’ve had an increase in the frequency of my eye tics and a new incidence of mouth tics — especially as the day wore on — that on some days is very difficult to deal with. Then, a month ago I thought that maybe it’s the Clonidine that is causing this, so I decided to change the way I take the drug by taking half of my daily dose during the day — but only starting in mid-afternoon — and taking the other half at bedtime.
The results so far of this change: Well, the increase in the frequency of my eye tics and my “never-had-before” mouth tics have both virtually vanished, and all other tics and symptoms are controlled just like before I made this change in the way I take the drug.
Also, because I now take half of my daily dose at bedtime I am sleeping better with fewer awakenings, and along with taking less Clonidine during the day I am more alert during my waking hours. So I am still getting the same 24-hour dose, but now I only start taking it in mid-afternoon as opposed to early morning and half of my daily dose is taken at bedtime.